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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d3d999f69096b3918200d3637f4157374db650d6f0f977037a944fe22dc221' 
  AND token = 'pwF4nBZy3Q4yaj+8ZV6sf9hc8nOtrEN6rRR0Lri41fU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}