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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c925f162a39e03891df733fcffa5fa176c0a50d32e90e6de0f0be36094129e2' 
  AND token = 'NW5zk50GOktjeSH23SuN08nDzb7E13kfZYLLwIuDbHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}