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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed64036d8fbd5bc5af64747aad5e052bf1922cfa0a964a7ce1b071cb55db1849' 
  AND token = 'zX2lFU0jixZusBFZS9zbs6Wq70uFQGVvrR0lIsB/Rds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}