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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56268d8b9aebc83a03ace28bb218ac39f70d9ffebf1aa124c1a9980b85680796' 
  AND token = 'ouWvMrcErT4KYIM9qbHq0XFBN3Nc9FxWrRY3iDpV2cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}