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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e0a6b3ff2aceb9d2e9b18f00f4718dc9c1034b2c01a5fc6308779cc392a7458' 
  AND token = '0ABj5NHY3cgGFFrgpE9eQHlbhoCLoO/DOsJ/DxTlmJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}