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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8910b9f3d9b9dd327b52cb26308da7bcb2e7590b7537576e9f9b3293386f436' 
  AND token = '1Yd4dF0dKEomaUpE0CNV9AYz4xfOHrbln6zkvRKa6GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}