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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f15b1764883fddd6fce7d5995934705cb5cb4d7347f7e5e8e58bf5961a285ea1' 
  AND token = 'pAg3wvW+FrSVCFAifEYUw8QW5r4x4C4QxmLUNS7Jqog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}