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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787eac4b46af1ac325610e3a298a8e31ddd659a7d8db10a690e2e985188a9411' 
  AND token = 'ctNhocb1OLS1ebRV9hNSi/EDSYxE1Es3UNqOmMSco+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}