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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2873a77443bf0503591dfc38715cc23b88f33222f4ab38dbb6b2841cd4fd6d36' 
  AND token = '9iTUzVnHBZ1ndmnSUdEW1D09W9EuGIsfZSjuccG9Xyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}