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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e333097d99dbbc63af1b31991523dd0f0d5a64c67cc0fdb28d7b779819fbb6d5' 
  AND token = 'R/nxz5M/D3J/xIGLY3iRh1+1JALrQcedz0p4fAT+lXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}