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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63745e951b6c27fb7333aa2b995ceee9561c2db5bb0206a3ddc42b7204aac4af' 
  AND token = 'sLXciqkU8dUTJlL9WmNa+IbM9RlkmiQ+LsbKTY8pAg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}