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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381144e826d0ce89363af0fe5eceb262645cc48fcdaed81ebb053603df32961c' 
  AND token = 't8FQBhxp6AvfLaF28sHWfS2+8kJJXqscpSu6GzSp6B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}