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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70d2a3c1f0376204012af6fc30fe4a0ff26db8b579b05330a817d59b3a60be62' 
  AND token = 'P9M97yfam+GARjSuATmxfrmPjmGUdMDfcqlYMzvbYRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}