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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed7a365ed84d1a465b450c6a0bcd184c31d57a2b27584c822c0a8e5a01db7bb' 
  AND token = 'eDhP0MwobQhPu2o7sDWOL2KMU0JUEuFG9Fa0Q2cAWzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}