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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07b5d7901e8601f638a9a1e757e817b17385d4f57bee45e1ed48a83294c1da7f' 
  AND token = 'fCyOSHeFNZGC8uzldAzzH5h+ehMcJkcpONEsaIBjQUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}