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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd6422c6e4fd1675534c1db9f41b2825b6ea48e92f66de50c14fdd09cfa80543' 
  AND token = 'ymeDzTU4nRw2jg/A4EtohTVx/TzTwJOieNkElrj+f1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}