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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980661d7f450a53d36ef0ad13952b1087231aa0daff793426d5a95ae9fbb0a18' 
  AND token = 'DV1Zf8DMRLP2QcIaJHLSmmUE8oP/4AWL3sR4D/3gKd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}