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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e963f2981bf522d76305d7db35c213e50033e1824de4d6f2a2f4560ace75fd' 
  AND token = '+TD5rUwpex8tYRTswfuxyt1sFoz8GPWIdhGB/ZvOv5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}