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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449dbb92c0daaae0d169ed9ca983603f965866a48de52f2528a151e382079a84' 
  AND token = '9Y5pAxVGGHVJzV88wT0qP6Fx2FjVjf1Uj5dN1DSVIhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}