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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22545a2bc5003d5f943df018235c9fa6436c3498d9945d477b8e1826664bb2ff' 
  AND token = 'NzApDCRDRtvuQl5zNMWSNh4ZRI18I+rMRaoajAoqAfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}