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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b3a5c36224921edff564ec4d7f4ee7ca643dfb78292dd47ae9097c7820e9ac' 
  AND token = 'xlE2X5LZCmJdjN79WWtwnzwvhNg1ccisdKmWFkGImpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}