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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7e1934724d9bb8badf5656e73ecdbe3ef76454e7db93934b75e681f72057d1' 
  AND token = '/FJjSeaiB83Md0Fr1GaF/FnN2jeluLl2SaZnJZaSGmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}