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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7c480bb1c66112f3cf43c94b5e7fd1bf0fae6a8240004769c6d284cc0c4dc1' 
  AND token = 'euqKWr8PR6K7vVY39C6vJRQWhYctR2W11RLfRVcd7NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}