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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d1a8ade4de3b3e3d9a6c6bc4707cda497b1d14ded87ffd5e601be63bc90023' 
  AND token = 'M19CYTBQ1PgKBN9mRFlI+lj+tflB2VkA6TctEm+T1j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}