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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c72eef5362c24be2254b619b52cbc2a0ef868fd167e9e0b494e7c9c6e243aa' 
  AND token = 'a+8zs6CuouQzI+jwl1gtPljTIRPCjjsKx+0MM/aQQcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}