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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ebeea40b29dc6a4f38fffe6604c43cb3ef2baa0c7f53d5217b50e40a02f7e1' 
  AND token = 'RwMALISQ8EbG4sTXwbf0fBSASMObZCW18dSjPnMtv20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}