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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746021ee05ab916bdbc141fbc6e0e4619f1a44e002e17ba75b7a7c6874dd906a' 
  AND token = 'wPVpMyeITgbGChHjtDh5e31iVH9cRM7V6fQE4K2+vc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}