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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8d0a2d63b2f60b21a02a2527380097600a02a00f534bc66d63d08ae08f5b11' 
  AND token = 'L4BjtigkPWfSL5WW9Oyi/h0W3p3vJ2wQRVlb5ftUYEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}