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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0b00029f2a1517bee29dde33876808e3211e632d4977e3cb962744cffc42021' 
  AND token = '+x+SbDQxrYxnKD8xDiU22tQl8UUeX3CQP8q3GuOQGaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}