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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef08266740c91b1924f535137a10f59f2a942cb1d17b52b7d6c5d670d87aa1d3' 
  AND token = '5TPs7/PsKIRWiGPTVsM6NZ0K3cIek7b/mRK9Misd0zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}