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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e2cd02c66ec8986b726e78f8cf7aa5afcf7200f3d023b39010edae68ef2089' 
  AND token = 'VcK5/c7L0oLkQDrTYXy+oGrQ1lpvHlya0bjmniezuXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}