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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbb38da0ab4f6aba6aff7920e4a7d4a17e1554fbb286ab0d5cfad0d325edb72f' 
  AND token = '+t9hsb9+xLMOBjvzk3MdmHHBK1T5gnT5TJHRxTVSBPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}