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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4403b5f4841518a68a9559d884c0878615519bd8dbfa2828376b60afc804c2' 
  AND token = 'r+Il1EEN98y/i/P6kvePXZt3uK+3urC8hQsRBnPYYVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}