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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745c589249027f1a09fcc1cfb98c070d38810f74c114c3d792c7cca320f0f1bd' 
  AND token = 'j874nQsesbQqHZmi+1iscPN6JR2OPVWMfkEIv7gsOjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}