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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be37ec7be4fc1a0dfa7fcef34b70487ad3ce67f5cd4516f15d1faf4d3019e645' 
  AND token = 'wInEvbM7cIr8w0wdqOQro0ZD54MbQqb0lYj2F2/m2rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}