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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d94b8ae6f75b51895b42f918f70fc3dc7184994085a49799006294aa977dc5e' 
  AND token = 'TjHWC3UoH1RfpJUapKYEofWBgqgdSRsJbP/pjzvka7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}