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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480d5a4650a49bb5a81dac4c63caa37bd6da8a425eb3e60c41b7698da2d3220a' 
  AND token = 'pVmwJydDs8zRANrMoE4q6ZW4xcuyKiO8kjlRyql4hUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}