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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a9c548e92ad45f90372ffb5c45b42fd9f727bb4a000b98d6b667244f1d17c19' 
  AND token = 'Zhq8xi0bx6n+OMMnp5Diy4/UW+X5EnaJvr69Mdfvjlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}