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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dd8da8a570ac90fbd1026eb858ee5c7de1cb296a05c57ba0bec6e7f6258d404' 
  AND token = 'JUhJttU7Pc5WFptxC67IGH2w/84Bs8a6tfXezd7dp4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}