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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5aabe518c3e72cc7f6e704b5de4cc844e130d20c2914fc31218e0ee046264aa' 
  AND token = 'bTdNMZC2y8nIbQnMNNqE5jCTbNvr/MCnrpSpeC8wr7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}