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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e609a1d12360406760664f4bf91b17eecccd3d67c8f7a86854b7fb905e32a15f' 
  AND token = 'ezwZhURzMNs4zmOl/N1Sv5RPbCfh60M+WrsUHjH0iJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}