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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a299ecde50bd1f4aba1645946b64920edc038cc9e1fe0c849c70d179d47b8ad7' 
  AND token = '//xt4r0D5GoM5KEt3FK+9e2rg6+FJxuCBiz24eqXWew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}