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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6be0af995d88d65e79b8de5e9bd47c0a98cfa095f2578d1bc0c6233bb3f4227' 
  AND token = 'LYmXmcAC+ol7ymCu2eKFpJvE8lO2EH4QQwv01B/eWWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}