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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aacedf3c17891e507060f8411bafbdff9423f8a17c6b26c750bf65e4feae01f1' 
  AND token = 'ysWu4AEEJtWsPOfhjpdLtkOruBuVQqEZlcVGDk4cFxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}