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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '578d9caed91898a56e368a550bc692f1f020f9d2cb45db0ea9bbbcf6cf8d9e41' 
  AND token = 'sCDX9rJDkuWz5G8Gyd+BiHbyRVZfje5qRsXJFpJjX80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}