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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '587b41407a51a753bf2641302a7439aeab94699904addb8f8245cd72d71d7094' 
  AND token = '+2ZdrhKi9aHEUM5SpC9dwwKd3KT+e0uJIoW2PLOCbK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}