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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef62cee2d67acb0c9000adfdb75e793bf0b12cd1aad542e436c068e99a64473f' 
  AND token = 'HUoDhRL5pn8Xl5Qno3ABbJK/BrhU9fsO2y3Gv0eRbd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}