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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1945badc65fcb350f2052e0da935a69c0ec6513f9624344bd9b521a4a2b3661f' 
  AND token = 'xxuMyxuNyz4R8ZeeHErkWNiigHelaOBXgtLWBj6qAWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}