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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3335107494d71f9747164897c27540a20a04fa759b05d63b806605abf00c70' 
  AND token = 'R8kCgTQ9eWEW0B3NTt30GXQyvozuLLxpKL607WeSeAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}