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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf2892d13aec2a661e085634299c1069211a34ca3538af9d2e8b20559b8d5e2' 
  AND token = '7zm+VAfNve6UgmEFtGF+deYOVmSbl7PRbeKLQC2N3M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}